Need Answers From Womens Hairloss About Spiro Time Frame

Discussion in 'Aldactone (Spironolactone)' started by Lisah, Oct 14, 2010.

  1. Lisah

    Lisah New Member

    Jjust got back a week ago from seeing Dr. Redmond.. like him and I really hope he knows what he's talking about(he could tell I questioned him in my mind) After all that we go through dealing with this shit I think we would question anyone about anything!!!!!!My question to users of Spiro( After I have been on a low dose for about 2.5 months ( Dr. Redmonds wants me to increase at least to a 100... Do you shed hair that quick? He said I shouldn't be because that isn't long enough to have it in my system... But I am shedding much more than I was 2 months ago ( nothing else has changed at all( so I'm thinking it's the Spiro?????? PLease let me know before I quit taking this stuff if that is normal or not??? I know that this is the most educated group to ask about this problem... Anyway all information appreciated.... Take care, Lisah:):)
  2. Dharma2

    Dharma2 Member

    Hi Lisa,

    I shed twice or three times as much hair right after I started spiro. My part widened so much. I was very disappointed but I kept thinking it would improve. Looking back I realize that it never really did and I now believe that the spiro caused continued hair loss. I am now off of every treatment and although I am still loosing some hair it is much better than when I was on meds. I feel alot better too. If I could change anything about my treatment it would have been to either not use spiro at all or only use it once the birth control kicked in. I don't know your entire story but trust your instincts not your fear. I wish you all the best. I read and believed in Dr. Redmond's treatment plan as well.

    Dharma:>
  3. kdwmw

    kdwmw New Member

    You should read my previous post about redmond & spiro. It's called what have I done to myself. It did not improve my hair & in fact put me at risk of kidney failure. He seems to treat all of us w/ the same remedy & practically assumes you have PCOS or Testosterone sensitivity. I am now seeing a specialist that has figured out that my hl is hormonal, but due to estrogen dominance caused by little to no production of progesterone. And here redmond was giving me more estrogen to help my hl after seeing the exact same labs. hmmmm.

    sorry if this is not what you want to hear, but I have little to no faith in him & put him in the category as just someone else taking advantage of us desperate for answers.

    oh & by the way, when my houston endo faxed him my blood work showing my potassium poisoning & called him to discuss my treatment, he never returned either of our calls. Dropped me like a hot potato. Very unethical IMOHO.
  4. A J P

    A J P New Member

    To Kdwmw, I have been on 100 mgs for about 2 1/2 weeks and my hair loss has almost stopped. Hope this helps!
  5. A J P

    A J P New Member

    Also no side effects!
  6. Lise

    Lise Member

    I took spiro for about two years. It helped improve some of the effects caused by being sensitive to testosterone (hirsutism) but ultimately didn't help with my hair. My hair has always gone through cycles where I shed more than other times (it is never down to a "normal" amount, just "bad" and "not quite as bad").

    I don't believe that spiro did me any harm, though it did not help me. I also believe in the theory behind why it will work for people with AGA. I think that for me it was just not strong enough. I also go to Redmond, but I had already done a fair amount of research and I went to him knowing that I wanted to be treated with anti-androgens and because I couldn't find anyone that would treat me where I was living.

    Nobody can predict how each individual will respond to a particular med. You would have to give it the 2-4 months before you knew if it was working or not. I wish you luck in making your decision. :)
  7. Runnergirl23

    Runnergirl23 New Member

    Dear Kdwmw,

    I am currently a patient of Dr. Remond's, have been for 8 months now. And I am very frustrated he put me on 200 mg of spiro, 2.5 mg of Finasteride and put me back on Yasmin. My hair has improved some but my body is a mess - extreme weight gain, no energy, hot flashes (seriously, I'm 33!). But Dr. Redmond dismisses all of these symptoms and basically tells me that there is nothing that can be done unless I want to try Yaz at 20mcg of estrogen instead of 30mcg. I am very curious about what type of specialist you are seeing. Could you shar some more of your story. I can't continue taking all of this - the BC pills especially, my testosterone levels and DHEA are now below normal - no wonder I am having extreme muscle fatigue - my weight training workout that use to be OK are killing me now. Would love to hear what you are currently taking, what is working, etc.

    Thanks!
  8. A J P

    A J P New Member

    spiro

    Hi Runnergirl. My doctor in Atlanta has me on 25. mgs. twice a
    day. Also, I take a hair vitamin that is called HairGain by Therapro.
    He also has me on 5000 mgs. of biotin, 800 mgs of folic acid, and flax seed
    meal. I put this in my smoothies 2X a day for total of 53 gm. a day. I also walk about 2 miles a day. that always helps me. Hope this helps!
    Last edited: Sep 26, 2011
  9. A J P

    A J P New Member

    I also don't pay an arm and a leg for my treatment. Dr. Edmond Griffin,
    Dermatology Associates of Atlanta. Hair loss sprecialist for men and women.
  10. A J P

    A J P New Member

    Don't lift too much weight. That's what's putting your weight on. Try cross training
    and lots of cardio!
  11. Cassy

    Cassy Member

    I also spent a year seeing Dr. Redmond. He put me on spiro. My Hair went from shedding 100 a day to over 300. My periods totally stopped and I lost 20 pounds. He insisted it was not the spiro and upped the dose. I took myself of the spiro and my periods came back as did the weight but the hair never did and it has been 10 years since that experience. Dr. Redmond dismisses everything you tell him which in my view makes for a bad doctor. Has anyone tried topical spiro? What did it do?
  12. Moonchild

    Moonchild New Member

    Spiro can definitely cause hair loss- mostly at higher doses!! If your hair sheds on it, STOP IT.

    Spiro works not by lowering testosterone levels in your blood, but by stopping the symptoms that arise from high levels of testosterone. So you still have the androgens in your blood, you just won't notice side effects from it.

    Spiro increases potassium in your body, which can kill you, and make you fatigued, short of breath, and all kinds of other things.
    It also is a diuretic, and drains your body of salt and sodiums, and throws your electrolyte balances all out of whack. This contributes to TONS of fatigue, confusion, dizziness, light headedness, increased thirst, increased urination, and can cause kidney problems.

    I was on Spiro for a little over a year- after every dose increase, more of my hair fell out faster, and easier, and only slowed when I started to take birth control pills.

    I was up to 200 mgs for 3 months and I began to get bald patches on my head! I stopped it immediately and the shedding seems to have slowed.

    I took Yaz once, and it slowed my hair loss significantly. I was really impressed. Yaz is a good choice because it has more synthetic estrogen- ethynil estradiol- than most other birth controls, and it is coupled with another synthetic hormone- drospirenone- which is a type of anti-androgen that is not as aggressive as spironolactone.
  13. Moonchild

    Moonchild New Member

    If you guys have any questions at all, please don't hesitate to message me and I will tell you everything I know!
  14. Tracy C

    Tracy C New Member

    For the benefit of everyone reading this it is very important to note that shedding is a necessary evil that is associated with every treatment for hair loss that actually works. Shedding needs to happen for treatment to work. The hair in the damaged hair follicles shed as those damaged hair follicles are returning to normal. Once those damaged hair follicles have returned to close to normal, the shedding stops. This can take a long time and stopping a treatment because of shedding is usually a mistake. Shedding is an indication that a treatment is working - not an indication that a treatment is failing. This persistent false notion is preventing a lot of women form adhering to treatments for their hair loss.

    With that said, it is also important to note that although Spironolactone obviously does help a lot of women resolve their hair loss, it is not appropriate for all causes of female hair loss. The cause of my hair loss is purely androgenetic alopecia. Spironolactone is appropriate for me and it has helped me, but for a woman whose cause is different, Spironolactone may not help at all – or make the problem worsen.

    It is much more difficult for doctors to determine what is causing a woman to lose her hair. It is very important to see a doctor who specializes in treating hair loss - and there is no harm in seeking second and third opinions from other doctors who specialize in treating hair loss.
  15. Cassy

    Cassy Member

    Lisah
    I posted a while ago but just found something out. The new endo i saw said the reason i lost so much hair on spiro is because it also blocked my estrogen. He knows this because MOST women will have menstral periods closer together on spiro. I on the otherhand had NO periods for the whole year i was on spiro. If it stops your periods get off of it . If you still have periods give it a shot.
  16. Tracy C

    Tracy C New Member

    Good observation. This makes sense to me.
  17. homegirl

    homegirl Member

    Spiro

    I read about it on WEB MD yesterday. It is a carcinogen.
  18. Tracy C

    Tracy C New Member

    I was surprised to read your post because I would have expected my doctor would have told me that if it were true. So I read what WebMD says about Spironolactone. WebMD does not say it is a carcinogen.

    http://www.webmd.com/drugs/drug-628...id=6288&drugname=spironolactone Oral&source=2


    I did some further digging and found this statement from multiple souces:


    Here is a statement taken from a paragraph in WebMD about Spironolactone:


    Spironolactone is not appropriate for everyone. Posting inaccurate information about any medication is never appropriate for anyone.
    Last edited: Dec 26, 2011
  19. homegirl

    homegirl Member

    Spiro

    Everyone should read the consumer information that is provided with any drug. Spiro test in mice have shown various forms of cancer. Although the dosage given to mice is highe than in humans, spiro can still cause cancer.

    According to various medical research unnecessary use of Spiro is not recommended.
  20. homegirl

    homegirl Member

    spiro

    Spironolactone is associated with an increased risk of [[hemorrhage|bleeding]] from the [[stomach]] and [[duodenum]], but a causal relationship between the two has not been established.<ref>{{cite journal | title=Spironolactone and risk of upper gastrointestinal events: population based case-control study | journal=Brit Med J | year=2006 | author=Verhamme KMC, Mosis G, Dieleman JP, ''et al.'' | volume=333 | issue=7563 | pages=330&ndash;3 | doi=10.1136/bmj.38883.479549.2F | pmid=16840442 | pmc=1539051 }}</ref> Because it also affects [[androgen receptor]]s and other steroid receptors, it can cause [[gynecomastia]], menstrual irregularities and testicular atrophy. Other side effects include [[ataxia]], [[erectile dysfunction]], [[drowsiness]], and [[rash]]es. A [[carcinogen]]ic effect has been demonstrated in rats, see below. Spironolactone has been shown to be [[immunosuppression|immunosuppressive]] in the treatment of [[sarcoidosis]].<ref>{{cite journal | title = Aldactone in the treatment of sarcoidosis of the lungs | journal=JZ Erkr Atmungsorgane. | year=1977 | author=Wandelt-Freerksen E. | volume=149 | pages=156–9 | pmid = 607621 | accessdate = 2007-05-02 | issue = 1}}</ref>
    Spironolactone often increases serum [[potassium]] levels and can cause [[hyperkalemia]], a very serious condition. Therefore, it is recommended that people using this drug avoid potassium supplements and salt substitutes containing potassium.<ref>{{cite web | title = Advisory Statement | publisher = Klinge Chemicals / LoSalt | url = http://www.losalt.com/docs/lo_salt_web_advice.pdf | format = pdf | accessdate = 2007-03-15 |archiveurl = http://web.archive.org/web/20061115185827/http://www.losalt.com/docs/lo_salt_web_advice.pdf <!-- Bot retrieved archive --> |archivedate = 2006-11-15}}</ref> Doctors usually recommend periodic screening of serum potassium levels and some patients may be advised to limit dietary consumption of potassium.
    Research has also shown spironolactone can interfere with the effectiveness of [[antidepressant]] treatment. The drug is actually (among its other receptor interactions) a mineralocorticoid (MR) antagonist, and has been found to reduce the effectiveness of antidepressant drugs in the treatment of [[major depression]], it is presumed, by interfering with normalization of the [[hypothalamic-pituitary-adrenal axis]] in patients receiving antidepressant therapy.<ref>Holsboer, F. The Rationale for Corticotropin-Releasing Hormone Receptor (CRH-R) Antagonists to Treat Depression and Anxiety. J. Psychiatr. Res. 33, 181–214 (1999)</ref>
    ===Carcinogenicity===
    Studies of spironolactone and the related compound [[potassium canrenoate]] (which, like spironolactone, metabolizes to [[canrenone]]) in rats for one- to two-year periods show an increase in carcinogenesis in the thyroid gland, testes, liver, breasts, and myelocytic leukocytes. Mammalian cells, depending on the presence of metabolic activation, show mixed results for mutagenicity ''in vitro''.<ref>{{cite web | title = Spironolactone RX Monograph | publisher = Sandoz Inc. | url = http://dailymed.nlm.nih.gov/dailymed/fdaDrugXsl.cfm?id=2479&type=display | accessdate = 2007-05-02}}</ref> Doses relative to body weight were 10 to 150&nbsp;mg per kg, which is ten to 500 times higher than normal doses for treating humans. In light of this research, [[Sandoz]] has recommended that unnecessary use of spironolactone be avoided.